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Cytokine Storm

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Cytokine Storm

Smooth Brain Studios · Published by Smooth Brain Studios

Last updated 29 Sept 2026

Cytokine Storm is a retro survival horror set inside a coma patient's body. Battle parasites, viruses, and a defective immune system to wake yourself up. Explore a surreal biological world where you must use your wits, weapons, and unique costumes to survive grotesque locations and puzzles.

Free to PlayComing SoonDJCTQ 141 DLC available ↗Full Controller Support

Free

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Action, Adventure, Free To Play · 2027 · More free games

About this game

Cytokine Storm is for fans PSX and PS2 survival horror, taking place entirely within the fractured biological systems of a woman fighting for her life. After a catastrophic medical event slips you into a deep coma, your consciousness materializes inside your own anatomy. To wake up, you must explore a grotesque, surreal interpretation of your body's vital systems, repairing the damage from the inside out before your time runs out.

Core Features:

  • Classic Retro Horror Nostalgia: Experience fixed camera angles, atmospheric lighting, and tense exploration designed to evoke the golden age of 32-bit survival horror.

  • A Dream-like Biological Setting: Navigate through varied, anatomical environments. Explore the forgotten beaches surrounded by extracellular fluid, the vibrant forest of the lungs, the pulsing vessels of the cardiovascular system, the red alert command center of a fried brain, and much more.

  • The Enemy Within: Your enemy is your own body. Battle vicious manifestations of invasive parasites, mutating viruses, and a hyper-aggressive, defective immune system that views your own consciousness as a foreign threat.

  • Outfits, Weapons, and Abilities: Explore your environment thoroughly and spend your resources wisely, as ammo is scarce. Discover unique costumes and match your active abilities and weapons to specific enemy types and environmental hazards.

  • Knowledge is Key: Solve cryptic puzzles using real-world medical knowledge. Understanding how different immune cells behave and interact in the human body will be the ultimate key to defeating them.

System Requirements

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Minimum

Minimum:
  • Requires a 64-bit processor and operating system
  • OS: Windows 10/11
  • Processor: Intel Core i3
  • Memory: 2 GB RAM
  • Graphics: Integrated Graphics
  • DirectX: Version 10
  • Storage: 2 GB available space

Recommended

Recommended:
  • Requires a 64-bit processor and operating system
  • OS: Windows 10/11
  • Processor: Intel Core i5
  • Memory: 4 GB RAM
  • Graphics: NVidia 1070 GTX
  • DirectX: Version 11
  • Storage: 3 GB available space

Supported Languages

English*
*languages with full audio support

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