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Plague Doctor: Life in Pestilence

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Plague Doctor: Life in Pestilence screenshot 1
Plague Doctor: Life in Pestilence Announcement Trailer trailerWatch trailer on Steam ↗

Plague Doctor: Life in Pestilence

PST Games · Published by PST Games

Content notice: Contains graphic depictions of historical medical procedures, including incisions, sutures, and blood, which may be unsettling for some players. Additionally, NPCs may perish from disease or poisoning.

Last updated 28 Sept 2026

From an unknown quack to a reputable Plague Doctor, watch the plague unfold before your eyes. Gather ingredients, brew remedies, expand your clinic, and perform surgeries alone or up to 4 player co-op. Will you uphold the Hippocratic Oath... or watch the world rot and darken with every death.

Free to PlayComing SoonDJCTQ 14Co-opFull Controller Support

Free

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Adventure, Indie, Simulation · More free games

Step into the role of a Plague Doctor during an outbreak. Gather ingredients, perform surgeries, and decide whether to uphold the Hippocratic Oath or let the world rot. Expand your clinic in solo or up to four-player co-op mode.

About this game

Appointed by the royal court to a remote village, you begin your journey as an unknown doctor. Build your reputation from a suspected quack to a reputable Plague Doctor, all while witnessing the spread of the plague day by day.

Step outside the safety of the village walls into an open world filled with natural resources. Travel to lush fields, navigate deep caves, and traverse dense forests to locate rare medicinal herbs, mushrooms, and minerals.

Identify and refine your gathered ingredients. Experiment with mixtures to discover potent medicinal properties, creating treatments that range from simple potions and pills to complex ointments and experimental injectable serums.

Every patient tells a story. Listen to their plight, examine their bodies for symptoms, and establish a diagnosis. Your treatments require steady hands, ranging from basic remedies to invasive surgeries and medieval practices.

Will you uphold the Hippocratic Oath, or decide who gets to live and who doesn’t? Choose carefully. The world responds dynamically to your success and failure. With every untreated patient and every death, the environment decays: homes fall into disrepair, fires break out, the weather turns turbulent, and nature itself withers.

Immerse yourself in a village where every NPC has a unique life, schedule, and behavior. Get to know them as you treat them, or watch them succumb to sickness, or perhaps, to your own malpractice.

Whether you bear the burden of the plague alone or share the task in 4-player co-op, the work never ends. However, when the pressure mounts, you can always find a moment of peace in the tavern, play the lute, or throw some dice.

System Requirements

Will my PC run this? →

Minimum

Minimum:
  • Requires a 64-bit processor and operating system
  • OS: Windows 10 64-bit
  • Processor: Intel Core i5-8400, AMD Ryzen 5 2600
  • Memory: 16 GB RAM
  • Graphics: NVIDIA GeForce GTX 1060 (6GB), AMD Radeon RX 580
  • DirectX: Version 12
  • Storage: 15 GB available space

Recommended

Recommended:
  • Requires a 64-bit processor and operating system
  • OS: Windows 10 64-bit
  • Processor: Intel Core i7-11700K, AMD Ryzen 7 5800
  • Memory: 32 GB RAM
  • Graphics: NVIDIA GeForce RTX 3060 (12GB), AMD Radeon RX 6600
  • DirectX: Version 12
  • Storage: 15 GB available space

Supported Languages

English*, French*, Italian*, German*, Spanish - Spain*, Japanese*, Korean*, Simplified Chinese*, Traditional Chinese*
*languages with full audio support

Latest news

  • AnnouncementsOfficial

    Thank you for 50 000+ Wishlists!

    It's been a little over 2 weeks since we announced Plague Doctor: Life in Pestilence and we are incredibly humbled and grateful for the amazing interest you have shown for the game.We received a lot of questions, so we compiled this short FAQ: What kind of game is it?Plague Doctor: Life in Pestilence is a truly immersive sim. We want players to step into a living, breathing world and feel like they are actually a Plague Doctor in turbulent medieval times.Is there magic or other fantasy elements?No. The game is grounded in reality. There are no spells or magic potions.How historically accurate is the game?We are trying to make the game as historically accurate as possible. However, if there are mechanics that would enhance the gameplay we will take creative liberties to distort the historic accuracy for a more engaging and fun experience.The world is viewed through the eyes of how people and physicians saw it back then. Treatments and afflictions that they believed worked in a certain way, will work in the same way in the game, even if we know now, in modern times, that they are ineffective.In what time period does the game occur?The game starts shortly before the plague's arrival and spread in Europe. We don't have a specific date, but the events happen around 1340-1360.Since the game starts before the plague, when will I get to play as a plague doctor?Players start as an unknown doctor. With the passage of time news will reach the player about a deadly disease getting closer and closer to the town they are in. Eventually the plague arrives at which point the players are tasked with becoming a plague doctor. The shift from a simple physician to a plague doctor marks a major turning point in the gameplay experience.Will there be a demo?Yes, there will be a demo when we feel the game is polished and ready to be shared. We will also be conducting public playtests during development.Can I play alone?Absolutely. The game can be played alone or with up to 3 friends in 4 p...
    Read full article on Community Announcements (Cioclod)

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