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Genome Guardian 2

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Genome Guardian 2

Alpherior · Published by Alpherior

Very Positive — 96% positive (433 reviews) · 100 achievements

Last updated 28 Sept 2026

COMBINE WEAPONS in the microscopic shooter with macroscopic depth. BUILD YOUR NANOBOT from hundreds of parts. SURVIVE the microbial onslaught once more in this psychedelic dive to the Abyss, full of mutations, minerals, anomalies and powerup polyps. SHMUP mode turns it into a vertical shoot 'em up!

Early AccessDJCTQ lFull Controller Support
-30%

£9.44

£13.49

Lowest price we've ever recorded

View on Steam

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£9.44£13.49

Price history

5 Sept 2026Lowest: £9.44 · Highest: £9.444 Oct 2026

Action, Indie, RPG, Early Access, Casual · 2026 · More £5 - £15 games

Explore the microscopic world of Genome Guardian 2, where you craft your nanobot from hundreds of parts and battle through mutations and anomalies. Dive into this unique action-RPG with early access features and survive the microbial onslaught.

About this game

Dive back into the microscopic world, radiating with bioluminescent life and unspeakable horrors.

Research permanent upgrades to survive a variety of microbes & modes in this massively expanded follow-up to Genome Guardian.

Build your own biomechanical death machine from different parts to define how it shoots, behaves & moves!

Make stationary turrets, psychic water sprinkler motorbikes, or maybe a dual-wielding fidget spinner Gundam.

  • Easily recreate your favourite turrets from the first game…or combine em' all into one frankenstein monstrosity

  • Save/Load 24 loadouts

  • Paint & Pattern customization

Pair DNA nucleotides A (rapidfire), C (precision), G (spread), T (explosive) to discover 70 hybrid bioweapons!

  • Shotgun + Bomb mix explosives with spread for Blast Shotgun!

  • SMG + Pistol make an accurate, fast-firing Scout Rifle!

  • Blast Shotgun + Scout Rifle = something a whole lot crazier!

  • 20-minute runs you can save & resume at any time + improved Endless Mode

  • Complete side objectives during runs for extra cash

  • Mine mineral deposits for resources

  • Trigger powerful Gadget active abilities

  • Test discovered weapons in the Database

  • 100 bassy electronic tunes with in-game Jukebox accessible any time + Streamer Mode

  • Auto aim/fire toggles

  • Localization in 10 languages

  • Full rebinding for keyboard & gamepad

  • 400% better performance/framerate on high & low-end PCs

  • Accessibility for colourblindness, motion sickness & arachnophobia

  • 100 Steam achievements

  • Cloud Save

  • Plays great on Steam Deck!

System Requirements

Will my PC run this? →

Minimum

Minimum:
  • Requires a 64-bit processor and operating system
  • OS: Windows 10
  • Memory: 4096 MB RAM
  • Storage: 1000 MB available space

Recommended

Recommended:
  • Requires a 64-bit processor and operating system
  • OS: Windows 10
  • Memory: 4096 MB RAM
  • Storage: 1000 MB available space

Supported Languages

English*, French*, Italian*, German*, Spanish - Spain*, Japanese*, Korean*, Portuguese - Brazil*, Russian*, Simplified Chinese*
*languages with full audio support

Latest news

  • Patch NotesOfficial

    Update 0.9.1

    🚨 "THE FULL RELEASE UPDATE" arrives 11 OCT🔄 CHANGESDRAFT Mode: It's now impossible for 2 offered Genes to be identical. (it was rare, but it happened)"Chronos" Guardian + "Accelerator" Mod: added a SETUP DIVE button warning stating regarding this (useless) combo.🔨 FIXESDaily Dive:a number of build combos that shouldn't be generated were getting generated. This will likely change the current Daily Dive into something entirely new.attempting to continue a savedDaily Dive from a previous play session now works."Chronos" Guardian: Spinning Microbes would face in the direction they're travelling while time is frozen."Fusion" Core: Genes that modify Firerate would make the Damage stat change when added to Explosive + Flak weapons."Moon" Mod: Accuracy decreases would still make wiggly projectiles more wiggly (which it shouldn't).💖 Please add a review! They directly support GG2 / development 💖You know those sites like Patreon or that Buy Me A Coffee one? That's what reviews are to a game.Whether it's 30 paragraphs or 1 letter, they all directly influence Genome Guardian 2's success & exposure.
    Read full article on Community Announcements (Alpherior)
  • Patch NotesOfficial

    THE DAILY DIVE UPDATE

    Or "THE URACIL UPDATE". Maybe I should have called it that.Indeed, Daily Dive has returned better than ever, and as of this update, you can now finally stop bugging me about "U". Of course, if neither of those things particularily interest you, there's also a bunch of new Guardians, Parts and Mods for ya.Everything below has unlock conditions listed in-game in the CHECKLIST but if you already meet their requirements, you'll instantly unlock them upon opening the game!DAILY DIVE REVAMPEDPeople really enjoyed Daily Dive in GG1, but they also all had a lot of the same complaints - primarily that there's little incentive to do them, and that they're often "unwinnable" (literally - ex. the turret & perk combo would instantly kill you). I've addressed each of those to make for a much-improved experience.each Daily Dive feature 3 modifiers (many of which are exclusive to Daily Dive)they're always Depth 5, but completing them for the first time grants an Enzyme (which lets you unlock anything you pick in the CHECKLIST)the builds it generates are carefully constructed to prevent "impossible dives" (unlike in GG1 lul), but still expect a decent challenge!you can play them even if you don't have the featured partsUnlocked after achieving victory at Depth 5 in any mode (not stated in-game)🚨 if you play the first-available Daily Dive (for day 240/365) you'll notice the Barrel makes one of the Mods completely useless - future Daily Dives won't have situations like this (and this Daily Dive is still very doable). Not sure if there's any more "make useless" combos but if people find em' I'll fix em'.URACIL (THE 5TH DNA LETTER) IS HEREYes, I really did it...well, kinda.I've made it clear that the 70 weapon roster won't expand, but: You're gonna start seeing rare white U DNAs in the SHOP. They aren't like the other DNA letters... They fit into DNA slots, but add 1 Gene slot!Suppose you're using the default Motherboard - 4 DNA slots, 3 Gene slots. U DNA makes all of these possible:AAA...
    Read full article on Community Announcements (Alpherior)
  • Patch NotesOfficial

    Update 0.8.2

    🚨 "THE DAILY DIVE UPDATE" releases 28 AUG (in about 3 weeks!)🚨 "THE FULL RELEASE UPDATE" releases 11 OCT⚖ BALANCE"Snare" Guardian: Damage +50% → +60%.🔄 CHANGESSETUP DIVE Button Warnings:"Tractor" Barrel + "Tempest" Guardian: Tempest is designed around Knockback builds but Tractor barrel disables Knockback."Tractor" Barrel + "Gloves" Mod: Gloves won't buff Knockback since Tractor Barrel disables Knockback."Tractor" Barrel + "Magnet" Mod: Magnet does nothing since Tractor Barrel disables Knockback.Hover Text "TIP"s: None of them were appearing in-game for Mods that have a newbie "TIP" text line set (note that you won't see these anyway if you've used the Mod many times).RECORDS Menu: Now properly shows values in the Trillions, and formats numbers better (ex. "1234K" now displays as "1.23M"). This also affects damage numbers during dives.🔨 FIXESRECORDS MENU:"BESTS" stats would sometimes decrease.Some values under "STATS" were accummulating twice as fast (this can't retroactively doublely-increased stats)."Tractor" Barrel + "Disc" Bracket: was producing weird behaviour when used with Hitscan weapons.DRAFT Mode: discovering a new weapon would sometimes result in the Skip & Reroll button dissappearing for the remainder of the run."EVASION FROM CHIPS CAN'T EXCEED 50%!" Chip-add warning was appearing when trying to add the wrong Chip.Sometimes, locked shop items would get replaced with DNA Letters - this was flying under my radar for a long time.Pausing a dive (returning to Main Menu in SHOP) with SKIP SHOP enabled would effectively reroll the items in the shop when you resume the dive.It was possible to unlock stuff (and get achievements for) completing DEPTH 5 in any Mode without ever having done so.🎨 FAN ARTSanguine by glungus (based on the in-game Sanguine Guardian)💖 Please add a review! They directly support GG2 / development 💖You know those sites like Patreon or that Buy Me A Coffee one? That's what reviews are to a game.Whether it's 30 paragraphs or 1 letter, they al...
    Read full article on Community Announcements (Alpherior)
  • Patch NotesOfficial

    Update 0.8.1

    🚨 "THE DAILY DIVE UPDATE" releases 28 AUG🚨 "THE FULL RELEASE UPDATE" releases 11 OCT⚖ BALANCEREDACTED Guardian: REDACTED, because it was so insanely busted, especially with Armour/Shield builds (still is pretty busted)🔄 CHANGESREDACTED Guardian: There's now a one-time SETUP DIVE button warning that states REDACTED when using this Guardian in MINER Mode."MINER" Mode:"BOMBARDMENT!" Powerpolyp won't damage the purple Abyss Deposits (the ones that hurt you when broken). Everything else still will though!slightly increased area of effect for Freeze & Explosive Deposits.🔨 FIXESREDACTED Guardian: the REDACTED part of the Lives count no longer fades out when Lives = 0."Disc" Bracket:Projectiles would instantly vanish if Velocity was 10."Compressor" Mod: now works with this as expected."Seismograph" Mod: fixed a number of cases where the Size/Velocity modifier swap wasn't being applied."Mercy" Endless Mutation: it's supposed to prevent you from dealing Damage while at full Health, and now it does so consistently and affects Deposits.SETTINGS:Menu Animation: in 0.8.0, it was preventing other animations from occurring too.Potato Mode: was supposed to also disable projectile trails, and now it does.Weapon ACGT "Chromaelstrom": explosions are now tinted red for Crits.Proximity Weapons...:...with Bounce:fixed cases where they'd do no Damage if their explosion size was tiny.now triggers explosions when hitting Deposits....with Pierce:no longer deal Damage twice per hit.some text formatting stuff.💖 Please add a review! They directly support GG2 / development 💖You know those sites like Patreon or that Buy Me A Coffee one? That's what reviews are to a game.Whether it's 30 paragraphs or 1 letter, they all directly influence Genome Guardian 2's success & exposure.
    Read full article on Community Announcements (Alpherior)
  • Patch NotesOfficial

    THE DRAFT & MINER UPDATE

    First off: Really glad to see 𝔂'𝓪𝓵𝓵 liked THE JESTER UPDATE, and I can't thank you enough for all the reviews you guys left because of it 💖 (if you still haven't left one, now's the time boi)...but it's about time we got some new Modes, ain't it? One is like a massively-improved GG1 "CLASSIC", and the other is entirely new since it revolves around Deposits.Of course, no major update is complete without new mechanics, Guardians, Parts & Mods!Everything below has unlock conditions listed in-game in the CHECKLIST but if you already meet their requirements, you'll instantly unlock them upon opening the game!DRAFT MODE 🃏Genes have a chance to be RARE, EPIC or LEGENDARY (boosting stats or removing downsides).there's no heal button, bleaching, banishing, locking, storage, recycling, or moving anything around once picked! Everything's a permanent commitment.defense/survival-oriented builds are great in this Mode since you don't necessarily need to eliminate Microbes (since they don't drop Biomass). A new resource, "Skips", will let you skip shops if you don't like anything on offer - Studies and Deposits can drop Skips!MINER MODE ⛏your entire economy is based on what you can mine from deposits.there's a variety of brand new deposit types exclusive to this Mode (most will help, but some will hurt).there's also a chance for absolutely giant mega deposits 👀ZONESA surprise new feature: Every few waves, a "zone" will spawn that grants buffs while you're in it!Some sit in place (but are smaller), while others spin around the area or bounce off the walls.Just a fun little extra mechanic to spice things up.NEW GUARDIAN: REDACTED 💗REDACTEDNEW PLATFORM: LANDER 🌕drag & drop Nanobot to reposition (can't shoot while dragging)Speed 200Health Max +50%Inspired by a game from a friend of mine, Primordio. Surprisingly intuitive to use, and while it is moving, it's super fast. You just can't reposition and shoot microbes at the same time is all. This was originally going to be "Booster", but ...
    Read full article on Community Announcements (Alpherior)

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