
Screenshots

Watch trailer on Steam ↗Chromosome Evil 2
S.C. 16 BIT NIGHTS S.R.L., dovganovskiy · Published by S.C. 16 BIT NIGHTS S.R.L. · Official site ↗
Very Positive — 88% positive (269 reviews) · 10 achievements
Last updated 27 Sept 2026
Dive deep into this Lovecraft-inspired RTS survival for a second time. Assemble your strike team and manage your convoy. It's up to you to survive the onslaught of nightmares that are surely coming your way. Will you find the source of the darkness?
£7.95
£15.90Lowest price we've ever recorded
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Price history
RPG, Strategy · 2024 · More £5 - £15 games
Command your strike team in Chromosome Evil 2, an RPG-RTS from S.C. 16 BIT NIGHTS S.R.L., managing resources and surviving the relentless onslaught of cosmic terrors.
About this game
DISCORD
About the Game

An ancient Lovecraftian evil has returned to earth unleashing a deadly flesh organism upon humanity.
One by one the the governments and the infrastructures of humans fell.
In the Aftermath of these events, you are part of what's left of the army and it is up to you to ensure the survival of the human species.

During combat, you take control of your strike team ensuring they will fulfill their objectives and return safely by choosing the optimal equipment and best tactical approach.
real-time strategy controls
"turn-based" possibility with active pause command mode

As a commander, you will take control of a military convoy where you can:
decide the equipment of your strike team
assign personnel to different survival tasks
craft better equipment
research new technologies
choose the path you want the convoy to take
manage resource priority
train your personnel

Chapter 1 - introduction to the game lore and new game options
Chapter 2 - The journey begins, assemble your convoy
Chapter 3 - Open-World
Chapter 4 - Multiple endings + 2 different totally unique paths
Additionally, the game folder also contains a Map Editor.
Good luck Commander!
System Requirements
Will my PC run this? →Minimum
- Requires a 64-bit processor and operating system
- OS *: Windows XP or higher
- Processor: Pentium 4
- Memory: 8 GB RAM
- Graphics: Any
- DirectX: Version 10
- Storage: 1 GB available space
- Sound Card: Any
Recommended
- Requires a 64-bit processor and operating system
- OS: Windows 10
- Processor: Multicore processors
- Memory: 16 GB RAM
- Graphics: Any
- DirectX: Version 10
- Storage: 2 GB available space
- Sound Card: Any
Supported Languages
Latest news
AnnouncementsOfficial
16 BIT NIGHTS Game Showcase 2027
Hey Folks, Gather around the fire, we have some BIG news for you. We just started 4 coming soon pages for 4 new projects, yes, not 1, not 2, not 3, BUT 4! Want to know more ? Here is our official video news about it: While you are there, feel free to SMASH that YouTube subscribe button for future news, trailers, and devblogs.Now that the Phase 1: coming soon pages debut is finished, we are moving to Phase 2: Demo debuts, so now we work hard on creating the Demos for the 4 projects as best as we can.Here is a list of the 4 projects we are working on(more details about them in the YouTube video): And also you are all invited to our Discord for live chat: https://discord.gg/ak5zXQxR7D Cya on the battlefield, Commanders! Regards, Cristi P. - 16 BIT NIGHTSRead full article on Community Announcements (conradproteus)Patch NotesOfficial
Chromosome Evil 2 BIG UPDATE + News New Game
Hey commanders,Fast news:Before we move any further with the update on Chromosome Evil 2, I would like to make a call to action for our new "Horizon 1990" project. SMASH that wishlist button with no mercy :Be prepared commander, we are going to take you to the STARS !And now, big UPDATE on Chromosome evil 2We added even more extra content in the form of more challenge missions accessible from the game's main menu.Here, you will take a custom squad and face delicate situations in special scenarios.Good luck commanderRegards,Cristi P. - 16 BIT NIGHTSRead full article on Community Announcements (conradproteus)Patch NotesOfficial
BIG UPDATE + News
Hey Players,HAPPY NEW YEAR!My partner prepared a secret surprise update for you on Chromosome Evil 2.A special Mission mode where you can play directly the evolution missions with a specific squad challenge.AND thats not all, he also added a special scripted custom mission made by a player from our Discord community.Credit for this mission goes to Robby from our Discord Community.If you guys used the map editor and made some interesting missions, you can send them to our Discord and if they are good, my partner will add them to the main game.NEWSSneak Peek Preview of one of our upcoming games.We aim for a mix of "Kingdom 2 Crowns" , "Until We Die" + a dash of "FTL."If you want to be updated with the progress and want to support us, you can check our social media:Twitter(X): https://x.com/16bitnightsBlueSky: https://bsky.app/profile/16bitnights.bsky.socialFacebook: https://www.facebook.com/16BITNIGHTS#And also our Steam Developer page for future game release notifications:https://store.steampowered.com/developer/16bitnightsGood luck Commander & A happy new year!Regards,Cristi P. - 16 BIT NIGHTSRead full article on Community Announcements (conradproteus)Patch NotesOfficial
Ukranian Language Update & News
Hey players,Kondratenko Yan Borysovych (Кондратенко Ян Борисович) voluntarily translated the game in the Ukrainian language and my partner updated the game.Thank you for your contribution!Meanwhile, we made some heavy progress on our Space Game project.You can check the latest devblog episode here:Regards,Cristi P. - 16 BIT NIGHTSRead full article on Community Announcements (conradproteus)AnnouncementsOfficial
NEWS #3 - New Game
Hey Folks,We come here to share with you the news about the current status and future of 16 BIT NIGHTS.Current status:We cook, we cook HARD.What do I mean by this?Well, we have not 1 but 3 projects in development.Project 1: New IPGameplay: A Mix of Kingdom with Xcom. Side view, real-time tactical, squad-based. Theme: Space, Astronauts, Experiment Philadelphia. Name: TBA, other details: TBAThe first online devblog is now live on YouTube, if you want to support us drop some love here:Dev Team: Me + Sadoff, my default partner from Chromosome Evil trilogyPreview:Project 2:New IPA unique deck-building game, mixing of survival elements with card-type combat. Theme: classic zombie(no mutations).Easy to play, hard to master.Dev Team: Me + Cavalie.ro, my old-time collaborator from TAURONOSPreview:Project 3:A game inspired by "Majesty" where you don't directly control your units, an interesting concept set in a post-apocalyptic world.Dev team: This is Sadoff project. he will do this by using the art pack from the old Chromosome Evil, meaning this will be a top-down strategy type of game experience.We hope that we will be able to deliver all 3 games, all things are subject to change at the moment, but the direction is pretty straightforward.Regards,Cristi P. - 16 BIT NIGHTSRead full article on Community Announcements (conradproteus)






